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Saffron strands

SF3 DAY Formula

Sourced for calm, mood and focus.

A saffron-led daily formula with clinically relevant support ingredients, built for a simple 30-day routine.

SF3 Daily Stress and Mood Complex sachet

Every ingredient. Every dose. Every reason why.

Saffron – The world's most studied plant for mood.

Saffron – The world's most studied plant for mood.

Key function 30 mg per daily serving
We use the same saffron extract studied in over 40 clinical trials for stress and mood — at the exact dose researchers used. Most saffron supplements use a fraction of this. Ours doesn't.

Based on 40+ clinical studies

L-Theanine – The natural calm found in green tea.

L-Theanine – The natural calm found in green tea.

Key function 200 mg per daily serving
Found naturally in green tea, L-theanine helps your brain shift into a calmer, more focused state — without making you sleepy. Studied to lower cortisol and reduce stress, at the dose we use.

Based on 20+ clinical studies

03 — Rhodiola rosea, the adaptogen with a paper trail

03 — Rhodiola rosea, the adaptogen with a paper trail

Key function 200 mg per daily serving
Standardized to salidroside and rosavins — the markers the EMA recognizes. Most rhodiola fails its own label; SF3® uses a fully authenticated extract studied for everyday stress-related fatigue, mental work capacity, and concentration under load.

Based on 40+ clinical studies

04 — Vitamin B3 (Niacin), the neurotransmitter cofactor

04 — Vitamin B3 (Niacin), the neurotransmitter cofactor

Key function 9.6 mg per daily serving (60% NRV)
Dosed to support normal psychological function — not to pad the label. Vitamin B3 is a required cofactor in the NAD+ pathway that powers neuronal energy and the synthesis of serotonin and dopamine. The foundation, not the hero.

Based on 40+ clinical studies

05 — Vitamin B6 (Pyridoxine), the serotonin precursor enzyme

05 — Vitamin B6 (Pyridoxine), the serotonin precursor enzyme

Key function 1.4 mg per daily serving (100% NRV)
The cofactor your brain uses to convert tryptophan into serotonin. B6 is the rate-limiting step in the conversion of 5-HTP into serotonin and L-DOPA into dopamine — the two neurotransmitters most directly implicated in mood regulation.

Based on 40+ clinical studies

Vitamin B9 + B12 – The duo behind a steady mood and steady energy.

Vitamin B9 + B12 – The duo behind a steady mood and steady energy.

Key function B9 200 μg + B12 2.5 μg per daily serving
These two always work as a pair. Together, they keep your mood chemistry running and your nervous system fueled — the quiet engine behind feeling like yourself, all day.

Based on 40+ clinical studies

Vegan friendly
No added sugar
Non-GMO

Source referenced in the SF3 formula research. Click below to open the journal on its own site.

Open on the journal site

The science

Built on 86 clinical studies

Every ingredient in SF3 traces back to published, peer-reviewed research — at the doses studied, for the outcomes that matter.

86
Clinical studies
12,400+
Participants
18
Peer-reviewed journals
6
Active compounds

The researchers behind our formula

SF3 is built on the work of independent scientists who have published the foundational research on our active compounds.

Dr. Adrian Lopresti

Dr. Adrian Lopresti

PhD, Clinical Psychologist · Murdoch University

Lead author, 2025 RCT on saffron and mood (n=202)

Dr. Philippa Jackson

Dr. Philippa Jackson

PhD, Neuroscientist · Northumbria University

Lead author, 2021 RCT on saffron, stress and HRV

Dr. Shinsuke Hidese

Dr. Shinsuke Hidese

MD PhD, Psychiatrist · NCNP Tokyo

Lead author, 2019 RCT on L-theanine and stress

Filter studies

Saffron · RCT

n=202. 12 weeks. Mood lifted.

The largest saffron RCT to date showed significant reduction in DASS-21 depression scores at 28mg/day vs. placebo.

Lopresti et al., 2025 — The Journal of Nutrition

Saffron · RCT

Stress hit. The body recovered faster.

Saffron 30mg improved mood and heart rate variability under acute psychosocial stress over 8 weeks.

Jackson et al., 2021 — Frontiers in Nutrition

L-Theanine · RCT

200mg. 4 weeks. Calmer baseline.

L-theanine reduced stress-related symptoms and improved sleep quality and executive function in healthy adults.

Hidese et al., 2019 — Nutrients

Saffron · RCT

4 weeks. Measurable change.

128 healthy adults saw improved mood, stress and anxiety scores at 28mg/day of clinical saffron extract.

Kell et al., 2017 — Complementary Therapies in Medicine

L-Theanine · RCT

One dose. Lower cortisol.

A single 200mg dose of L-theanine raised alpha brain wave activity and blunted the cortisol response to acute stress.

Evans et al., 2021 — Neurology and Therapy

Rhodiola · RCT

2×200mg. 14 days. Less anxiety.

Rhodiola rosea extract reduced anxiety, stress, anger and confusion scores in mildly anxious adults.

Cropley et al., 2015 — Phytotherapy Research

References describe independent research on the individual actives at the doses studied. The researchers listed are not affiliated with SF3 and do not endorse the finished product.